The Effect of Nigella Sativa Oil Supplementation and Four Weeks Aerobic Training on CRP and Physical Ability of Inactive Young Women

Document Type : Original Article

Authors

1 Assistant Prof, Dept of Sport Sciences, Faculty of Humanities, University of Qom, Qom, Iran.

2 Associate Prof, Dept of Biochemistry, Faculty of Biochemistry, Qom University of Medical Sciences, Qom, Iran

3 MSc Student, Dept of Exercise Physiology, Faculty of Humanities, University of Qom, Qom, Iran.

10.22123/chj.2023.347472.1912

Abstract

Introduction: Exercise training and some supplements, such as Nigella Sativa, significantly change inflammatory factors and fat percentage. The present study aims to determine the effects of four weeks of aerobic exercise and the use of Nigella Sativa Oil Supplementation separately or together on fat percentage and C-reactive protein inflammatory index in inactive women.
Materials and methods: This semi-experimental research was conducted in the form of pre -post-test and the field method. For this purpose, 40 inactive women were selected and randomly divided into four equal groups, including exercise-supplement, exercise-placebo, supplement, and control. Aerobic exercises during four sessions and Nigella Sativa Oil Supplementation in the form of a 1000 mg capsule were given daily after lunch. Fat percentage and CRP were measured before and 48 hours after the last exercise and supplementation protocol. Statistical analysis was performed by paired t-test and analysis of covariance at a significance level of p<0.05.
Results: Covariance analysis showed a significant decrease in CRP levels (p<0.001); also, a significant difference was observed between the control group and the experimental groups and between the placebo group and the exercise-supplement and supplement groups (p<.0/05). The intragroup results indicated a significant decrease in CRP in three experimental groups before and after four weeks of training and supplementation (p<0.01). The difference in fat percentage between groups was not significant. There was a significant decrease in fat percentage in the placebo group before and after four weeks of training and supplementation (p<0.05).
Conclusion: It is recommended to use the black seed oil supplement alone and in combination with aerobic exercise to improve the effect of aerobic exercise in reducing inflammatory injuries. In order to have a better effect of aerobic exercise in decreasing inflammatory injuries, Nigella Sativa Oil can be used alone and in combination with aerobic exercise.

Keywords

References

  1. Lorenz D, Morrison S. Current Concepts in periodization of Strength and Conditioning for the Sports Physical Therapist. IJSPT 2015; 10(6), 734–747.
  2. Askari f, basiri m k, basiri m m, torabi s, gholamfarkhani s, mohareri m, et al. Age of natural menopause and compare The incidence of its early complications in menopause transition stages in women from Gonabad city. HMS 2012; 17(4).42-48. [Persian]
  3. Jessica CL, Anderson J L, Carlquist J F, Roberts RF, Horne BD, Bair TL, et al. Comparison of differing C-reactive protein assay methods and their impact on cardiovascular risk assessment. AJC 2005; 95(1): 155-158. 
  4. Church TS, Barlow C.E, Earnest CP, Kampert JB, Priest EL, Blair, S.N. Association between cardiorespiratory fitness and C-reative protein in men. ATVB 2002; 22:1869-1876
  5. Rawson, E.S., Freedson, P.S. and Ockene, I.S. Body mass index, but not physical activity, is associated with C-reactive protein.  MSE 2003; 35(7):1160-1166.
  6. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. NEJM 2005; 352: 1685-1695.
  7. Stevenson, E.T., Davy, K.P. and Seals D.R. Hemostatic, Metabolic, and androgenic risk factors for coronary heart disease in physically active and less active postmenpausal women. ATVB 1995; 15(5); 669-677.
  8. Kelley GA, Kelley KS. Effects of aerobic exercise on Creactive protein, body composition, and maximum oxygen consumption in adults: a meta – analysis of randomized controlled trials. MJ 2006; 55: 1500-1507.
  9. Zhao J, Xu F, Huang H, Wang L, Tan W, Li C et al. Evaluation on anti-inflammatory, analgesic, antitumor, and antioxidant potential of total saponins from Nigella glandulifera seeds. ECAM 2013.
  10. Okita K, Nishijima H, Murakami T, Nagai T, Morita N, Yonezawa K, et al. Can exercise training with weight loss lower serum Creactive protein levels? ATVB 2004; 24 (10):1868-73.
  11. Sharieatzadeh S M, MalkyRad A, Hovaida R, Rahzani K, AghaJohary M, Fazli D. The effect of Nigella sativa on oxidative stress. JSUMS 2011; 12 (4):21-26. [Persian]
  12. M. s. Nima, Z. Farhad. Sample Size in Medical Research: an applied approach. ASRP 2017; 29-31.
  13. Hemostatic, Metabolic, and androgenic risk factors for coronary heart disease in physically active and less active postmenpausal women. ATVB1995;15(5); 669-677
  14. Bijeh SAH, K Hejazi. The Effect of Aerobic Exercise on Serum C - Reactive Protein and Leptin Levels in Untrained Middle-Aged Women. IJPH 2012; 41(9):36-41. [Persian]
  15. Dabidi Roshan V, Fallah Mohammadi Z, Barzegar Zadeh H. The effect of shortterm supplementation of glutamine on A im- munoglobulin in saliva of active males following an exhaustive activity. OJ 2005; 2:7-15. [Persian]
  16. Blake G.J, Ridker PM. Novel clinical makers of vascular wall inflammation. CR 2001; 89(9):763-71.
  17. Vallianoud , Natalia Rahele Tavakolya,b , Arman Arabc, Cain C.T. Clarke , Amir Hadif et al. The effect of Nigella sativa L. supplementation on serum C-reactive protein: A systematic review and meta‐analysis of randomized controlled trials. CTHM 2019;45(6):49-53.
  18. Salem M. Immunomodulatory and therapeutic properties of the nigella sativa L. seed. IIP 2005;43(5):68-78.
  19. Arikawa AY, Thomas W, Schmitz KH, Kurzer MS. Sixteen weeks of exercise reduces Creactive protein levels in young women. MSSE 2011;43(6):1002-9.
  20. Kaatabi H, Bamosa AO, Lebda FM, Al Elq AH, Al-Sultan AI. Favorable impact of Nigella sativa seeds on lipid profile in type 2 diabetic patients. JFCM 2012;19(3). 155-170.
  21. Jackson AS, Pollock ML, Ward A. Generalized equations for predicting body density of women. MSSE 1980;12:175–181.
  22. Gomes‐Filho IS, Freitas Coelho JM, da Cruz SS, Passos JS, Teixeira de Freitas CO, Aragão Farias NS et al. Chronic periodontitis and C-reactive protein levels. JP 2010; 82(7):969-78.
  23. Huffman KM, Samsa GP, Slentz CA, Duscha BD, Johnson JL, Bales CW et al. Response of high-sensitivity C-reactive protein to exercise training in an at-risk population. AHJ 2006; 152 (4):793-800.
  24. Nayebifar sh,A fzalpour M,Sagheebjou M,Shirzaee P. The effect of aerobic and resistance trainings on serum c- reactive protein, lipid profile and body composition in overweight women. MCJ 2011.,4(32):186-196. [Persian]
  25. Namazi N, Larijani B, Ayati MH, Abdollahi M. The effects of Nigella sativa L. on obesity: A systematic review and meta-analysis. JEP 2018; 12 (219). 173-81. [Persian]
  26. Mousavia M, Ali Sheikhia  H, Varkaneha,d  M, Zarezadehb,d  J,Rahmanic Ai. Effect of Nigella sativa supplementation on obesity indices: A systematic review and meta-analysis of randomized controlled trials. CTM 2018; 1 (38):48-57. [Persian]
  27. Farzaneh, Nia FR2, Mehrtash, Mirmoeini, Jalilvand. The Effects of 8-week Nigella sativa Supplementation and Aerobic Training on Lipid Profile and VO2 max in Sedentary Overweight Females. IJPM 2014; 5(2):210.

 

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